Day 1
Registration and poster setup 10am - 11am
11am-12pm
11:00-11:15 Welcome and opening remarks
11:15-11:30 Safia Omer (University of Guelph)
β-Tubulin Mutation Disrupts Cell-Cell Junction and Lysosomal Distribution via Dysregulation of Cytoskeletal Motors
11:30-11:45 Firyal Ramzan (University of Waterloo)
Mistargeted by Lipidation: S-acylation and protein mislocalization in Neurodegeneration
11:45-12:00 Ellis Chartley (University of Guelph)
Exploring BDNF-induced DNA damage as a regulator of the neuronal plasticity effector Arc.
Lunch 12-1pm
1pm-3:10pm
1:00-1:05 Session welcome
1:05-1:55 Keynote 1: Julie Brill (The Hospital for Sick Children and the University of Toronto)
1:55-2:10 Maria Eugenia Perez Collado (The Hospital for Sick Children)
Identification of Endoplasmic Reticulum-Dense Core Vesicles Membrane Contact Sites in Human iPSC-Derived Neurons
2:10-2:25 Seth MacKenzie (Western University)
Live-cell Manipulation of Subcellular Phosphatidic Acid Levels
2:25-2:40 Karan Ishii (University of Toronto)
Calcium signaling by mechanogated channels and ER locally synchronize collective focal adhesion dynamics in migrating cells
2:40-2:55 Josephine Esposto (Trent University)
Functional roles of SodE in regulating cell adhesion, metal ion trafficking and multicellular development in Dictyostelium discoideum
2:55-3:10 Alex Daiejavad (University of Toronto)
Marker Project: approaches for analyzing sub-cellular compartment phenotypes in S. cerevisiae using single-cell data from high content screening
Posters and Vendor Show 3:15-5:15pm
5:25-6:30pm
5:25-6:30 Session welcome
5:30-5:45 Sihat Salam (York University)
Epigenetic effect of CBP/p300 inhibition on histone H3 phospho-acetylation crosstalk in the regulation of immediate early genes
5:45-6:00 Kerenza Cheng (Toronto Metropolitan University)
One hand clapping: novel analysis shows asymmetry of the DNA replication fork, imaged through R-ODD-BLOBS
6:00-6:15 Samantha Laville-Dupuy (McMaster University)
Oxidative stress drives centrosomal re-localization of DNA repair proteins: High-content analysis reveals centrosome-based DNA damage response deficits in Huntington disease
6:15-6:30 Maral Janan (York University)
Tubulin deacetylation is required for spindle organization and chromosome movement during cell division
Dinner and Reception 7pm-10pm
Day 2
Registration and poster setup 8:00-8:30am
8:30-9:40am
8:30-8:35 Session welcome
8:35-8:50 Katarina Micovic (Toronto Metropolitan University)
Discovery and Characterization of Inhibitors of the Actin-Regulatory MICAL Monooxygenases
8:50-9:05 Victoria Fletcher (Brock University)
Evaluating Novel PIN1 Inhibitors for Subtype-Specific Targeting of Notch Signalling in Breast Cancer
9:05-9:20 Byeong Yeop Lee (University of Toronto)
Functional Role and Therapeutic Targeting of miR-19b-1 in Acute Myeloid Leukemia
9:20-9:35 Kseniia Golik (Toronto Metropolitan University)
Akt around and find out: how clathrin nanodomains modulate Akt isoform engagement
Vendor show and coffee break 9:40-10:50am
10:50am-12:30pm
10:50-11:50 Lightning talks
Lauren Viola (University of Toronto)
Yasmeen Alshehabi (University of Waterloo)
Katherine Moncada (Toronto Metropolitan University)
Shelby Bryan (Trent University)
Sylvia Xu (University of Toronto)
Jayson Capistrano (University of Guelph)
Kevin Dockery (University of Toronto)
Tiana Clarke (Toronto Metropolitan University)
Cecilia Gimenez (University of Toronto Scarborough)
11:50-12:05 Jiahao (Chris) Li (University of Toronto Scarborough)
Proximity Biotinylation Maps Dynein–Dynactin Interactors in Pathogen-Infected Host Cells
12:05-12:20 Irina Zhitnyak (University of Toronto)
Distinct actin isoform networks drive different stages of phagocytosis
12:05-12:20 Serene Moussaoui (University of Toronto Scarborough)
Macrophages control Aspergillus fumigatus hyphae through an adapted phagocytic program
Lunch 12:40-1:30pm
Posters and Vendor Show 1:30pm-3:30pm
3:45pm-5:40pm
3:45-4:35 Keynote 2: Éric Lécuyer (Institut de recherches cliniques de Montréal)
4:35-4:50 Maria Narciso (Toronto Metropolitan University)
PIKfyve Inhibition Impairs Lysosome-Mitochondria-ER Interactions Leading to Disruption of Mitochondrial Dynamics and Function
4:50-5:10 Caitlin Oh (Western University)
Defining the Role of Membrane Lipids in Mitochondrial Quality Control
5:10-5:25 Jaskaran Singh Hora (Queen’s University)
Increased Expression and Phosphorylation of Mitochondrial Fission Factor (MFF) Promotes Proliferative Phenotypes in Pulmonary Arterial Hypertension t
5:25-5:40 Cordula Enenkel (University of Toronto)
Metabolically regulated proteasome supramolecular organization in situ Metabolically regulated proteasome supramolecular organization in situ
Awards and closing remarks 5:45-6:00pm