The Ontario Cell Biology Symposium will bring together researchers from around the province with the aim of creating new research opportunities and fostering new collaborations. This Symposium aims to provide a forum for students and postdoctoral fellows to present their research. This meeting will cover important topics in cell biology, including signal transduction, metabolism, organelles, cellular architecture, cellular trafficking and advanced microscopy, with a portion of the meeting dedicated to translational studies and emerging methodologies. We aim to create an inclusive environment for this meeting, and one that will feature diverse participants.
In 2020, the Ontario Cell Biology Symposium has moved to an online format. The meeting (all online) will be held from Monday, June 1 to Friday, June 5th, with talks available through an online platform on each of the 5 days from 11:30am to 1:30pm.
PROGRAM
June 1: Cytoskeleton, cell migration and cell division
11:30 Welcome and session introduction
11:40 Katheryn Rothenberg, IBBME - University of Toronto
Rap1 regulates actomyosin dynamics to drive rapid wound repair
12:00 Thomas Panagiotou, Department of Molecular Genetics, University of Toronto
Determinants of Intercellular Bridge Maturation
12:20 Jack Bauer, IRIC - Université de Montréal
Developmental regulation of germline syncytium organization in C. elegans
12:40 Fernando Valencia, Cell and Systems Biology, University of Toronto
Activation of Actin Elongation Factor Dia1 by Mechanical Force Protects the Cytoskeleton from Damage and Facilitates Stress Fiber Repair
1:00 Jonah Burke-Kleinman, U of Toronto
N-Cadherin mimetic peptides inhibit vascular smooth muscle cell migration
1:20 Breakout sessions
June 2: Development, stem cells and disease
11:30 Session introduction
11:35 Celeste Suart, Biochemistry & Biomedical Sciences, McMaster University
Ataxin-1 is signalled to DNA damage by ATM kinase
11:55 Isabelle Grenier-Pleau, Queen's University
Investigating the role of extracellular vesicles in hematopoietic stem cell maintenance
12:15 Melissa Iazzi, Ryerson University
Examining the CFTR interactome upon mutation and drug exposure
12:35 Arman Shekari, Psychiatry and Behavioural Neurosciences, McMaster University
The retrograde transport of BDNF and ProNGF diminishes with age in basal forebrain cholinergic neurons
12:55 Robert Huber, Biology, Trent University
Molecular networking in Batten disease: Insights from the social amoeba Dictyostelium discoideum
1:15 Nadeem Murtaza, Biochemistry and Biomedical Sciences, McMaster University
Developing a neuronal protein interaction network for neurodevelopmental disorder associated genes using proximity-based proteomics
1:35 Breakout session
June 3: Cancer cell biology
11:30 Session introduction
11:35 Bre-Anne Fifield, Biomedical Sciences, University of Windsor
The atypical cyclin-like protein, Spy1, regulates mammary gland biology by altering checkpoint activation
11:55 Paola M. Dantonio, Dept. of Biomedical & Molecular Sciences, Queen’s University
Embryonic Protein NODAL Broadly Regulates the Breast Tumour Microenvironment by Reprogramming Cancer-Derived Secretomes
12:15 Krista Schleicher, Systems Biology, Lunenfeld Tanenbaum Research Institute
Ajuba loss initiates Head and Neck Cancer in a Notch-dependent mechanism
12:35 .Larasati, Department of Biology, University of Waterloo
A proline-rich Rif1 motif mediates interaction with Dbf4, promoting DNA replication and resistance to genotoxic stress
12:55 Hartland Jackson, Lunenfeld Tanenbaum Research Institute
The single-cell pathology landscape of breast cancer: tumour cells and their microenvironments
1:15 Breakout sessions
June 4: Cell Metabolism
11:30 Session introduction
11:35 Victoria Riccio, Cell Biology, Sick Kids
The deubiquitinase USP30 regulates peroxisome abundance by regulating pexophagy
11:55 Sadia Rahmani, Department of Chemistry and Biology, Ryerson University
Nutrient dependent regulation of Adapter Protein 2 (AP2) in clathrin-mediated endocytosis via N-acetylglucosamine modification
12:15 Amanda Bentley-DeSousa, University of Ottawa / Institute of Systems Biology
Investigating the AP3 complex: linking a rare syndrome to an ancient molecule
12:35 Xin Chen, Developmental and Stem Cell Biology, The Hospital for Sick Children
Targeting mechanosensitive ion channel PIEZO1 in brain tumors
12:55 Mireille Khacho, University of Ottawa
Mitochondrial shape changes regulate stem cells quiescence and fate decisions through metabolic communication to the nucleus
1:15 Breakout sessions
June 5: Cell biology of infection and immunity
11:30 Session introduction
11:35 Truc Losier, University of Ottawa
Bacterial outer membrane vesicles trigger pre-activation of an anti-bacterial response via AMPK signalling
11:55 Rachel Wilson, Physiology & Pharmacology, Western University
Regulation of hepatocyte lipid droplet formation under lipotoxic conditions by the marine compound didemnin B
12:15 Glenn Walpole, University of Toronto and SickKids
Stimulation of phosphatidylinositol-3,4-bisphosphate synthesis by the Salmonella Typhimurium effector SopB drives efficient host cell invasion
12:35 Shiraz Anwar, Ryerson University
Investigating the effects external stressors on lysosomal tubulation in macrophages
12:55 Tarannum Tasnim, Department of Microbiology & Immunology, Western University
Identification of the Signalosome and Signalling Pathway of the Efferocytic Receptor MERTK
1:15 Breakout sessions
ORGANIZING COMMITTEE AND CONTACTS
The organizing committee for the 2020 Ontario Cell Biology Symposium is:
Lesley MacNeil (McMaster University)
Robin Duncan (University of Waterloo)
Andrew Wilde (University of Toronto)
Peter Kim (SickKids)
Rene Harrison (University of Toronto Scarborough)
Jonathan Lee (University of Ottawa)
Michael Scheid (York University)
Andrew Craig (Queen's University)
Lisa Porter (University of Windsor)
Nica Borradaile (Western university)
Costin Antonescu (Ryerson University)
For more information, please contact