June 1-5, 11:30am-1:30pm each day
Online Zoom platform.

The Ontario Cell Biology Symposium will bring together researchers from around the province with the aim of creating new research opportunities and fostering new collaborations. This Symposium aims to provide a forum for students and postdoctoral fellows to present their research. This meeting will cover important topics in cell biology, including signal transduction, metabolism, organelles, cellular architecture, cellular trafficking and advanced microscopy, with a portion of the meeting dedicated to translational studies and emerging methodologies. We aim to create an inclusive environment for this meeting, and one that will feature diverse participants.

In 2020, the Ontario Cell Biology Symposium has moved to an online format. The meeting (all online) will be held from Monday, June 1 to Friday, June 5th, with talks available through an online platform on each of the 5 days from 11:30am to 1:30pm



June 1: Cytoskeleton, cell migration and cell division

11:30   Welcome and session introduction

11:40   Katheryn Rothenberg, IBBME - University of Toronto

            Rap1 regulates actomyosin dynamics to drive rapid wound repair

12:00   Thomas Panagiotou, Department of Molecular Genetics, University of Toronto

            Determinants of Intercellular Bridge Maturation

12:20   Jack Bauer, IRIC - Université de Montréal

            Developmental regulation of germline syncytium organization in C. elegans

12:40   Fernando Valencia, Cell and Systems Biology, University of Toronto

            Activation of Actin Elongation Factor Dia1 by Mechanical Force Protects the Cytoskeleton from Damage and Facilitates Stress Fiber Repair

1:00     Jonah Burke-Kleinman, U of Toronto

            N-Cadherin mimetic peptides inhibit vascular smooth muscle cell migration

1:20     Breakout sessions

June 2:  Development, stem cells and disease

11:30   Session introduction

11:35   Celeste Suart, Biochemistry & Biomedical Sciences, McMaster University

            Ataxin-1 is signalled to DNA damage by ATM kinase

11:55   Isabelle Grenier-Pleau, Queen's University

            Investigating the role of extracellular vesicles in hematopoietic stem cell maintenance

12:15   Melissa Iazzi, Ryerson University

            Examining the CFTR interactome upon mutation and drug exposure

12:35   Arman Shekari, Psychiatry and Behavioural Neurosciences, McMaster University

            The retrograde transport of BDNF and ProNGF diminishes with age in     basal forebrain cholinergic neurons

12:55   Robert Huber, Biology, Trent University

            Molecular networking in Batten disease: Insights from the social amoeba  Dictyostelium discoideum

1:15     Nadeem Murtaza, Biochemistry and Biomedical Sciences, McMaster University

            Developing a neuronal protein interaction network for neurodevelopmental disorder associated genes using proximity-based proteomics

1:35     Breakout session

June 3: Cancer cell biology

11:30   Session introduction

11:35   Bre-Anne Fifield, Biomedical Sciences, University of Windsor

            The atypical cyclin-like protein, Spy1, regulates mammary gland biology by altering checkpoint activation

11:55   Paola M. Dantonio, Dept. of Biomedical & Molecular Sciences, Queen’s University

            Embryonic Protein NODAL Broadly Regulates the Breast Tumour Microenvironment by Reprogramming Cancer-Derived Secretomes

12:15   Krista Schleicher, Systems Biology, Lunenfeld Tanenbaum Research Institute

            Ajuba loss initiates Head and Neck Cancer in a Notch-dependent mechanism

12:35   .Larasati, Department of Biology, University of Waterloo

            A proline-rich Rif1 motif mediates interaction with Dbf4, promoting DNA replication and resistance to genotoxic stress

12:55   Hartland Jackson, Lunenfeld Tanenbaum Research Institute

            The single-cell pathology landscape of breast cancer: tumour cells and their microenvironments

1:15     Breakout sessions

June 4: Cell Metabolism

11:30   Session introduction

11:35   Victoria Riccio, Cell Biology, Sick Kids

            The deubiquitinase USP30 regulates peroxisome abundance by regulating pexophagy

11:55   Sadia Rahmani, Department of Chemistry and Biology, Ryerson University

            Nutrient dependent regulation of Adapter Protein 2 (AP2) in clathrin-mediated endocytosis via N-acetylglucosamine modification

12:15   Amanda Bentley-DeSousa, University of Ottawa / Institute of Systems Biology

            Investigating the AP3 complex: linking a rare syndrome to an ancient molecule

12:35   Xin Chen, Developmental and Stem Cell Biology, The Hospital for Sick Children

            Targeting mechanosensitive ion channel PIEZO1 in brain tumors

12:55   Mireille Khacho, University of Ottawa

            Mitochondrial shape changes regulate stem cells quiescence and fate decisions through metabolic communication to the nucleus

1:15     Breakout sessions

June 5: Cell biology of infection and immunity

11:30   Session introduction

11:35   Truc Losier, University of Ottawa

            Bacterial outer membrane vesicles trigger pre-activation of an anti-bacterial response via AMPK signalling

11:55   Rachel Wilson, Physiology & Pharmacology, Western University

            Regulation of hepatocyte lipid droplet formation under lipotoxic conditions by the marine compound didemnin B

12:15   Glenn Walpole, University of Toronto and SickKids

            Stimulation of phosphatidylinositol-3,4-bisphosphate synthesis by the Salmonella Typhimurium effector SopB drives efficient host cell invasion

12:35   Shiraz Anwar, Ryerson University

            Investigating the effects external stressors on lysosomal tubulation in macrophages

12:55   Tarannum Tasnim, Department of Microbiology & Immunology, Western University

            Identification of the Signalosome and Signalling Pathway of the Efferocytic Receptor MERTK

1:15     Breakout sessions



The organizing committee for the 2020 Ontario Cell Biology Symposium is:

Lesley MacNeil (McMaster University)
Robin Duncan (University of Waterloo)
Andrew Wilde (University of Toronto)

Peter Kim (SickKids)
Rene Harrison (University of Toronto Scarborough)

Jonathan Lee (University of Ottawa)

Michael Scheid (York University)

Andrew Craig (Queen's University)

Lisa Porter (University of Windsor)

Nica Borradaile (Western university)

Costin Antonescu (Ryerson University)

For more information, please contact ontariocellbiology@gmail.com


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